| Identification | Back Directory | [Name]
7-(2,4-dinitrophenoxy)-4-methylchromen-2-one | [CAS]
314742-00-2 | [Synonyms]
7-(2,4-dinitrophenoxy)-4-methylchromen-2-one
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one
7-(2,4-dinitrophenoxy)-4-methyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-(2,4-dinitrophenoxy)-4-methyl- | [Molecular Formula]
C16H10N2O7 | [MDL Number]
MFCD01540118 | [MOL File]
314742-00-2.mol | [Molecular Weight]
342.26 |
| Chemical Properties | Back Directory | [Boiling point ]
496.4±45.0 °C(Predicted) | [density ]
1.492±0.06 g/cm3(Predicted) | [solubility ]
Chloroform: 30mg/mL; DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:2): 0.30mg/mL; DMSO: 5mg/mL | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one (Compound 1) is a fluorescent probe for the detection of hydrogen sulfide (H2S). 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has a low detection limit (4×10-6 mol/L), good selectivity and high sensitivity. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one shows almost no cytotoxicity at concentrations of 150 μg/mL. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has the excitation peak of 331 nm, and the emission peak about 385 nm in DMSO solvent. Upon the addition of increasing amounts of HS-, the fluorescence intensity increases obviously at about 392 nm[1]. | [References]
[1] Chen Y, et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci Rep. 2018 Nov 1;8(1):16159. DOI:10.1038/s41598-018-34331-9 |
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| Company Name: |
OTAVA chemicals
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416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
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