| Identification | Back Directory | [Name]
MYCOPHENOLIC ACID GLUCURONIDE | [CAS]
31528-44-6 | [Synonyms]
MYCOPHENOLIC ACID GLUCURONIDE
Mycophenolic Acid -D-Glucuronide
MYCOPHENOLIC ACID B-D-GLUCURONIDE
Mycophenolic Acid Glucosiduronate
Mycophenolic acid β-D-glucuronide ,98%
Mycophenolic acid-β-D-glucuronide solution
Mycophenolic acid-phenolic-beta-D-glucuronide
Mycophenolic acid-O-beta-D-glucuronide min. 97%
5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl -D-Glucopyranosiduronic Acid
5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl b-D-Glucopyranosiduronic Acid | [Molecular Formula]
C23H28O12 | [MDL Number]
MFCD08063739 | [MOL File]
31528-44-6.mol | [Molecular Weight]
496.46 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
98-100°C | [Boiling point ]
875.7±65.0 °C(Predicted) | [density ]
1.502±0.06 g/cm3(Predicted) | [Fp ]
2℃ | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
2.76±0.70(Predicted) | [color ]
White to Pale Beige | [Stability:]
Hygroscopic | [InChIKey]
BYFGTSAYQQIUCN-HGIHDBQLSA-N | [SMILES]
COc1c(C)c2COC(=O)c2c(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)c1C\C=C(/C)CCC(O)=O |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monoph
osphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. | [General Description]
A Certified Spiking Solution? for use in therapeutic drug monitoring analyses of serum or whole blood by HPLC or LCMS. The glucuronide, also known as MPAG, is the primary metabolite of the immunosuppressant mycophenolic acid and is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range. | [in vivo]
Mycophenolic acid glucuronide (intraperitoneal injection; 6 mg/mouse; once two days; 6 d) treatment reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model[2]. | Animal Model: | Swiss albino strain mouse implanted with Ehrlich ascites tumor cells[2] | | Dosage: | 6 mg/mouse | | Administration: | Intraperitoneal injection; 6 mg/mouse; once two days; 6 d | | Result: | Showed 76.8% tumor inhibition compared to the untreated control. |
|
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
11-20/21/22-36 | [Safety Statements ]
16-26-36/37 | [RIDADR ]
UN 1648 3 / PGII | [WGK Germany ]
2 | [HS Code ]
29389090 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|