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3153-55-7

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3153-55-7 Structure

3153-55-7 Structure
IdentificationBack Directory
[Name]

ORTHO-NORNUCIFERINE
[CAS]

3153-55-7
[Synonyms]

ORTHO-NORNUCIFERINE
O-demethyl nuciferine
(6aR)-5,6,6a,7-Tetrahydro-1-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-2-ol
4H-Dibenzo[de,g]quinolin-2-ol, 5,6,6a,7-tetrahydro-1-methoxy-6-methyl-, (6aR)-
[Molecular Formula]

C18H19NO2
[MDL Number]

MFCD01664604
[MOL File]

3153-55-7.mol
[Molecular Weight]

281.35
Chemical PropertiesBack Directory
[Melting point ]

195-197℃ (ethyl acetate )
[Boiling point ]

451.4±45.0 °C(Predicted)
[density ]

1.216±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

10.12±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].
[IC 50]

Human Endogenous Metabolite
[References]

[1] Ulrike Grienke, et al. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9. PMID:260352
Spectrum DetailBack Directory
[Spectrum Detail]

ORTHO-NORNUCIFERINE(3153-55-7)1HNMR
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