| Identification | Back Directory | [Name]
ML311 | [CAS]
315698-17-0 | [Synonyms]
ML311
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
2-((4-ethylpiperazin-1-yl)(4-(trifluoromethyl)phenyl)methyl)naphthalen-1-ol | [Molecular Formula]
C23H24F3N3O | [MDL Number]
MFCD02330695 | [MOL File]
315698-17-0.mol | [Molecular Weight]
415.45 |
| Chemical Properties | Back Directory | [Melting point ]
>94*C (dec.) | [Boiling point ]
515.7±45.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.38±0.50(Predicted) | [color ]
Yellow | [InChIKey]
NGAPBLRRJSKIRT-UHFFFAOYSA-N | [SMILES]
FC(F)(F)c1ccc(cc1)C(N4CCN(CC4)CC)c2c(c3ncccc3cc2)O |
| Hazard Information | Back Directory | [Uses]
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol is a selective inhibitor of the protein -protein interaction of Mcl-1 inhibitors and also a potential antitumor agents. Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity. | [Biological Activity]
Cell permeable: yes''Primary Target
Mcl-1''Reversible: yes | [IC 50]
Mcl-1; Bim | [storage]
Store at -20°C |
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| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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