| Identification | Back Directory | [Name]
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE | [CAS]
316173-57-6 | [Synonyms]
SCH 442416
2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidi
5-Amino-7-(3-(4-methoxyphenyl)propyl)-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine,2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]- | [Molecular Formula]
C20H19N7O2 | [MDL Number]
MFCD08703126 | [MOL File]
316173-57-6.mol | [Molecular Weight]
389.41 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [pka]
2.77±0.30(Predicted) | [color ]
light tan to tan | [InChI]
1S/C20H19N7O2/c1-28-14-8-6-13(7-9-14)4-2-10-26-18-15(12-22-26)19-23-17(16-5-3-11-29-16)25-27(19)20(21)24-18/h3,5-9,11-12H,2,4,10H2,1H3,(H2,21,24) | [InChIKey]
AEULVFLPCJOBCE-UHFFFAOYSA-N | [SMILES]
COc1ccc(CCCn2ncc3c2nc(N)n4nc(nc34)-c5ccco5)cc1 |
| Hazard Information | Back Directory | [Uses]
SCH 442416 is a potent and selective A2A adenosine receptor antagonist. | [Definition]
ChEBI: LSM-3027 is a member of triazolopyrimidines. | [Biological Activity]
Extremely selective adenosine A 2A receptor antagonist that binds to human and rat A 2A receptors with high affinity (K i values are 0.048 and 0.5 nM respectively). In vitro displays > 23000-fold selectivity for hA 2A over hA 1 and minimal affinity for hA 2B and hA 3 receptors (IC 50 > 10 μ M). | [Biochem/physiol Actions]
SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors. | [storage]
Store at RT |
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Sigma-Aldrich
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