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XMP-629 is an endotoxin inhibitor potentially for the treatment of impetigo and acne rosacea. | [Uses]
XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand[1][2]. | [References]
[1] Hancock RE, et, al. Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol. 2012 Mar 16;10(4):243-54. DOI:10.1038/nrmicro2745
[2] Bhopale GM. Antimicrobial Peptides: A Promising Avenue for Human Healthcare. Curr Pharm Biotechnol. 2020;21(2):90-96. DOI:10.2174/1389201020666191011121722 |
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