ChemicalBook--->CAS DataBase List--->316805-65-9

316805-65-9

316805-65-9 Structure

316805-65-9 Structure
IdentificationBack Directory
[Name]

XMP-629
[CAS]

316805-65-9
[Synonyms]

XMP-629
XOMA629
XOMA-629
XOMA 629
[Molecular Formula]

C67H93N15O11
[MOL File]

316805-65-9.mol
[Molecular Weight]

1284.55
Chemical PropertiesBack Directory
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

3.30±0.30(Predicted)
Hazard InformationBack Directory
[Description]

XMP-629 is an endotoxin inhibitor potentially for the treatment of impetigo and acne rosacea.
[Uses]

XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand[1][2].
[References]

[1] Hancock RE, et, al. Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol. 2012 Mar 16;10(4):243-54. DOI:10.1038/nrmicro2745
[2] Bhopale GM. Antimicrobial Peptides: A Promising Avenue for Human Healthcare. Curr Pharm Biotechnol. 2020;21(2):90-96. DOI:10.2174/1389201020666191011121722
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