| Identification | Back Directory | [Name]
PROSTAGLANDINS E2 METHYL ESTER | [CAS]
31753-17-0 | [Synonyms]
pge2methylester
ylester,stereoisomer
WGCXTGBZBFBQPP-ZYONDNFOSA-N
PROSTAGLANDIN E2 METHYL ESTER
PROSTAGLANDINS E2 METHYL ESTER
Prostaglandin E2 methyl ester
Prostaglandin E2 methyl ester Exclusive
9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, METHYL ESTER
7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoicacimeth
(5Z,13E,15S)-11α,15-Dihydroxy-9-oxo-5,13-prostadiene-1-oic acid methyl ester
[5Z,11α,13E,15S,(-)]-11,15-Dihydroxy-9-oxoprosta-5,13-diene-1-oic acid methyl ester
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, methyl ester, (5Z,11α,13E,15S)-
(Z)-7-[(1α)-2β-[(S,E)-3-Hydroxy-1-octenyl]-3α-hydroxy-5-oxocyclopentyl]-5-heptenoic acid methyl ester
(5Z)-7-[(1R)-2β-[(1E,3S)-3-Hydroxy-1-octenyl]-3α-hydroxy-5-oxocyclopentane-1α-yl]-5-heptenoic acid methyl ester | [Molecular Formula]
C21H34O5 | [MDL Number]
MFCD00133789 | [MOL File]
31753-17-0.mol | [Molecular Weight]
366.49 |
| Hazard Information | Back Directory | [Description]
Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 with enhanced lipid solubility. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) values of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue. | [Uses]
Prostaglandin E2 methyl ester (PGE2 methyl ester) is an lipophilic derivative analog of PGE2 (HY-101952). Prostaglandin E2 methyl ester has more central penetration ability than PGE2[1]. | [References]
[1] Strand JC, et al. Biological activity of the methyl esters of prostaglandin E2 and its (15S)-15-methyl analogue. Eur J Pharmacol. 1974 May;26(2):151-7. DOI:10.1016/0014-2999(74)90221-0 |
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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