ChemicalBook--->CAS DataBase List--->320337-48-2

320337-48-2

320337-48-2 Structure

320337-48-2 Structure
IdentificationBack Directory
[Name]

Lapatinib IMpurity 8
[CAS]

320337-48-2
[Synonyms]

Lapatinib Desmesylethylamino Hydroxy Imp
Des(sulfonylethyl)amino Hydroxy Lapatinib
Lapatinib Desmesylethylamino Hydroxy impurity
4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-(5-hydroxymethylfuran-2-yl)quinazoline
5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furanmethanol
2-Furanmethanol, 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-
[Molecular Formula]

C26H19ClFN3O3
[MOL File]

320337-48-2.mol
[Molecular Weight]

475.9
Chemical PropertiesBack Directory
[Melting point ]

>150°C (dec)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
[form ]

Solid
[color ]

Pale Yellow to Light Yellow
Hazard InformationBack Directory
[Uses]

Des(sulfonylethyl)amino Hydroxy Lapatinib is a compound related to drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
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