| Identification | Back Directory | [Name]
D-erythro-sphinganine (C17 base) | [CAS]
32164-02-6 | [Synonyms]
Sphinganine-C17
sphinganine (d17:0)
D-erythro-sphinganine (C17 base)
D-ERYTHRO-SPHINGANINE (C17 BASE);SPHINGANINE (D17:0) | [Molecular Formula]
C17H37NO2 | [MOL File]
32164-02-6.mol | [Molecular Weight]
287.48 |
| Chemical Properties | Back Directory | [Melting point ]
74-76 °C(Solv: acetonitrile (75-05-8)) | [Boiling point ]
433.1±25.0 °C(Predicted) | [density ]
0.931±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible | [form ]
A crystalline solid | [pka]
12.57±0.45(Predicted) | [InChI]
1S/C17H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h16-17,19-20H,2-15,18H2,1H3/t16-,17+/m0/s1 | [InChIKey]
KFQUQCFJDMSIJF-DLBZAZTESA-N | [SMILES]
OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC |
| Hazard Information | Back Directory | [Description]
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods. | [Uses]
Sphinganine-C17 is found in bovine serum. Sphinganine-C17 is a biomarker for assessment of delayed-type hypersensitivity and response to triptolide. | [Definition]
ChEBI: Heptadecasphinganine is an aminodiol and a sphingoid. | [storage]
Store at -20°C | [References]
[1] KARIN THEVISSEN . Fungicidal activity of truncated analogues of dihydrosphingosine[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 13: Pages 3728-3730. DOI: 10.1016/j.bmcl.2008.05.067
[2] STEFKA SPASSIEVA. Combination of C(17) sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism.[J]. Methods in enzymology, 2007, 434: 233-241. DOI: 10.1016/s0076-6879(07)34012-3
[3] FENG QU. Sphingolipids as new biomarkers for assessment of delayed-type hypersensitivity and response to triptolide.[J]. PLoS ONE, 2012: e52454. DOI: 10.1371/journal.pone.0052454 |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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