| Identification | Back Directory | [Name]
1,2-dioctanoyl-sn-glycero-3-phosphate (sodiuM salt) | [CAS]
321883-54-9 | [Synonyms]
08:0 PA
1,2-dioctanoyl-sn-glycero-3-phosphate (sodiuM salt)
1,2-dioctanoyl-sn-glycero-3-phosphate acid(sodium salt)
1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE (SODIUM SALT);08:0 PA
Octanoic acid (1R)-1-[(phosphonooxy)methyl]-1,2-ethanediyl ester monosodium salt | [Molecular Formula]
C19H35Na2O8P | [MOL File]
321883-54-9.mol | [Molecular Weight]
468.43 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
powder | [InChI]
1S/C19H37O8P.Na/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2;/h17H,3-16H2,1-2H3,(H2,22,23,24);/q;+1/p-1/t17-;/m1./s1 | [InChIKey]
ZNDNSOYDPUTHKQ-UNTBIKODSA-M | [SMILES]
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+] |
| Hazard Information | Back Directory | [Uses]
08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian target of rapamycin (mTOR) pathway signaling. | [Biological Activity]
Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 08:0 PA/C8-PA has the ability to affect the phosphorylation of mammalian target of rapamycin (mTOR) and the viability of gallbladder carcinoma cellsth at are treated with histone deacetylase inhibitors (HDACIs). |
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