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32222-00-7

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32222-00-7 Structure

32222-00-7 Structure
IdentificationBack Directory
[Name]

ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG
[CAS]

32222-00-7
[Synonyms]

BRADYKININ (TYR8)
(TYR8)-BRADYKININ
ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG-OH
L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Tyr-L-Arg-OH
N5-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-tyrosyl-N5-(diaminomethylene)-L-ornithine
[Molecular Formula]

C50H73N15O12
[MDL Number]

MFCD00076281
[MOL File]

32222-00-7.mol
[Molecular Weight]

1076.21
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[form ]

Solid
[pka]

3.32±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1].
[IC 50]

ERK1; ERK2
[References]

[1] Webb JG, et al. Bradykinin activation of extracellular signal-regulated kinases in human trabecular meshwork cells. Exp Eye Res. 2011 Jun;92(6):495-501. DOI:10.1016/j.exer.2011.03.009
[2] Wilson SR, et al. Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection. J Sep Sci. 2005 Sep;28(14):1751-8. DOI:10.1002/jssc.200500062
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