| Identification | Back Directory | [Name]
ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG | [CAS]
32222-00-7 | [Synonyms]
BRADYKININ (TYR8)
(TYR8)-BRADYKININ
ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-TYR-ARG-OH
L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Tyr-L-Arg-OH
N5-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-tyrosyl-N5-(diaminomethylene)-L-ornithine | [Molecular Formula]
C50H73N15O12 | [MDL Number]
MFCD00076281 | [MOL File]
32222-00-7.mol | [Molecular Weight]
1076.21 |
| Hazard Information | Back Directory | [Uses]
[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1]. | [IC 50]
ERK1; ERK2 | [References]
[1] Webb JG, et al. Bradykinin activation of extracellular signal-regulated kinases in human trabecular meshwork cells. Exp Eye Res. 2011 Jun;92(6):495-501. DOI:10.1016/j.exer.2011.03.009
[2] Wilson SR, et al. Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection. J Sep Sci. 2005 Sep;28(14):1751-8. DOI:10.1002/jssc.200500062 |
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