| Identification | Back Directory | [Name]
4-[acetyl(2-naphthylsulfonyl)amino]-2-bromophenyl acetate | [CAS]
324022-08-4 | [Synonyms]
EBNA1-IN-SC7
4-[acetyl(2-naphthylsulfonyl)amino]-2-bromophenyl acetate | [Molecular Formula]
C20H16BrNO5S | [MOL File]
324022-08-4.mol | [Molecular Weight]
462.314 |
| Hazard Information | Back Directory | [Uses]
EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research[1]. | [References]
[1] Lijun Jiang, et al. EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers. Theranostics. 2018 Oct 22;8(19):5307-5319. DOI:10.7150/thno.26823
[2] Ning Li, et al. Discovery of selective inhibitors against EBNA1 via high throughput in silico virtual screening. PLoS One. 2010 Apr 12;5(4):e10126. DOI:10.1371/journal.pone.0010126 |
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