| Identification | Back Directory | [Name]
3'-O-DMT-T-TNA | [CAS]
325683-89-4 | [Synonyms]
3'-O-DMT-T-TNA
1-(3’-O-[4,4’-dimethoxytrityl]-α-L-threofuranosyl)-thymine
1-(3'-O-[4,4'-dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-5-methyl- | [Molecular Formula]
C30H30N2O7 | [MOL File]
325683-89-4.mol | [Molecular Weight]
530.58 |
| Hazard Information | Back Directory | [Uses]
1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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