| Identification | Back Directory | [Name]
GERMACRONE | [CAS]
32663-51-7 | [Synonyms]
3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3Z,7E)- | [Molecular Formula]
C15H22O | [MDL Number]
MFCD00210050 | [MOL File]
32663-51-7.mol | [Molecular Weight]
218.33 |
| Hazard Information | Back Directory | [Uses]
cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1]. | [References]
[1] Zhao Y, et al. Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway. Mol Med Rep. 2021 Jun;23(6):452. DOI:10.3892/mmr.2021.12091 |
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| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-029-81138252 +86-173 9270 1263 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/ |
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
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