| Identification | Back Directory | [Name]
4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)- | [CAS]
326866-17-5 | [Synonyms]
FAAH inhibitor 1
Benzothiazole analog 3
FAAH inhibitor 1 (Benzothiazole analog 3)
4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)-
N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)-1-(thiophen-2-ylsulfonyl)piperidine-4-carboxamide | [Molecular Formula]
C24H23N3O3S3 | [MDL Number]
MFCD02167759 | [MOL File]
326866-17-5.mol | [Molecular Weight]
497.65 |
| Chemical Properties | Back Directory | [density ]
1.416±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
13.90±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM[1]. | [References]
[1] Wang, Xueqing; Sarris, Katerina; Kage, Karen; et al. Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors. Journal of Medicinal Chemistry (2009), 52(1), 170-180. DOI:10.1021/jm801042a
[2] Meyers, Marvin J.; Long, Scott A.; Pelc, Matthew J.; et al. Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds. Bioorganic & Med DOI:10.1016/j.bmcl.2011.08.055 |
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Musechem
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+1-800-259-7612 |
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www.musechem.com |
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