| Identification | Back Directory | [Name]
6-tert-Butyl-2,3-naphthalenedicarbonitrile | [CAS]
32703-82-5 | [Synonyms]
LABOTEST-BB LT00159322
6-tert-butyl-2,3-naphthalonitrile
2,3-Dicyano-6-tert-butylnaphthalene
6-tert-Butyl-2,3-dicyanonaphthalene
6-tert-Butyl-2,3-naphthalodinitrile
6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE
6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile
2,3-NAPHTHALENEDICARBONITRILE, 6-(1,1-DIMETHYLETHYL)- | [Molecular Formula]
C16H14N2 | [MDL Number]
MFCD00209558 | [MOL File]
32703-82-5.mol | [Molecular Weight]
234.3 |
| Chemical Properties | Back Directory | [Melting point ]
185-189 °C(lit.)
| [Boiling point ]
429.7±33.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [color ]
Pale Yellow to Light Beige | [Major Application]
diagnostic assay manufacturing
hematology
histology | [InChI]
InChI=1S/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3 | [InChIKey]
MKILROQBJOOZKC-UHFFFAOYSA-N | [SMILES]
C1=C2C(C=C(C(C)(C)C)C=C2)=CC(C#N)=C1C#N |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22 | [Safety Statements ]
36 | [WGK Germany ]
3
| [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites. | [Definition]
ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes. | [Biological Activity]
BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM. | [References]
[1] SHRIKANTA CHATTOPADHYAY. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.[J]. Cell reports, 2015, 10 5: 755-770. DOI: 10.1016/j.celrep.2015.01.017 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Struchem Co., Ltd.
|
| Telephone: |
0512-63009836 18994340901 |
| Website: |
http://www.beidapharma.com |
| Company Name: |
BePharm Ltd
|
| Telephone: |
400-685-9117 |
| Website: |
www.bepharm.com |
|