| Identification | Back Directory | [Name]
N-ACETYLPROCAINAMIDE | [CAS]
32795-44-1 | [Synonyms]
acekainid
acecainide
TIMTEC-BB SBB005970
n-acetyloprokainamid
N-ACETYLPROCAINAMIDE
N-ACETYLPROCAINAMIDE, 99+%
N-ACETYLPROCAINAMIDE USP/EP/BP
4-acetamido-N-(2-(diethylamino)ethyl)benzamide
4’-((2-(diethylamino)ethyl)carbamoyl)-acetanilid
4’-((2-(diethylamino)ethyl)carbamoyl)acetanilide
4-(acetylamino)-n-(2-(diethylamino)ethyl)-benzamid
4-(acetylamino)-n-[2-(diethylamino)ethyl]-benzamid
4-(Acetylamino)-N-[2-(diethylamino)ethyl]benzamide
Benzamide, 4-(acetylamino)-N-[2-(diethylamino)ethyl]- | [Molecular Formula]
C15H23N3O2 | [MDL Number]
MFCD00009052 | [MOL File]
32795-44-1.mol | [Molecular Weight]
277.36 |
| Chemical Properties | Back Directory | [Melting point ]
138-140 °C(lit.)
| [Boiling point ]
500.0±35.0 °C(Predicted) | [density ]
1.097±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
soluble1%, clear, colorless to faintly yellow (1N HCl) | [form ]
Solid | [pka]
14.54±0.46(Predicted) | [color ]
White to off-white | [Water Solubility ]
soluble 1%, clear, colorless to faintly yellow (1N HCl) | [Merck ]
13,20 |
| Hazard Information | Back Directory | [Originator]
Acecainide ,ZYF Pharm Chemical | [Uses]
antiprotozoal | [Definition]
ChEBI: A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine. | [Manufacturing Process]
1.0 g of p-amino-N-(2-diethylaminoethyl)benzamide is dissolved in
chloroform. A few ice cubes are added to the solution. Acetyl chloride is added
dropwise with stirring until no more white precipitate forms; the latter is
separated by filtering under suction. The precipitate is washed with cold
acetone and dried overnight in a vacuum oven at room temperature. The
product is dissolved in a minimum amount of hot isopropanol and allowed to
precipitate in the cold. The p-acetamido-N-(2-diethylaminoethyl)benzamide
hydrochloride, is recrystallized a second time from hot isopropanol, melting
point 190°-193°C.
The free base is obtained from the hydrochloride by dissolving the latter in
water, adjusting the pH to greater than 10 with dilute sodium hydroxide, and
adding an equal volume of benzene. After shaking in a separatory funnel, the
benzene layer is recovered and evaporated to dryness. So the p-acetamido-N-
(2-diethylaminoethyl)benzamide is obtained.
| [Therapeutic Function]
Antiarrhythmic | [General Description]
The relaxant effects of N-acetylprocainamide on bovine tracheal smooth muscle was studied. |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|