| Identification | Back Directory | [Name]
1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride) | [CAS]
328250-28-8 | [Synonyms]
R-DOTAP(DOTAP R-isomer )
1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride)
1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-, chloride (1:1), (2R)- | [MOL File]
328250-28-8.mol | [Molecular Weight]
698.54 |
| Hazard Information | Back Directory | [Uses]
1,2-Dioleoyl-3(R)-trimethylammoniumpropane chloride is a biochemical reagent. | [References]
[1] MEGAN CAVANAUGH TERP . Differential efficacy of DOTAP enantiomers for siRNA delivery in vitro[J]. International Journal of Pharmaceutics, 2012, 430 1: Pages 328-334. DOI: 10.1016/j.ijpharm.2012.04.017
[2] ELIZABETH A VASIEVICH Leaf H Weihsu Chen. Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccine.[J]. Cancer Immunology, Immunotherapy, 2011, 60 5: 629-638. DOI: 10.1007/s00262-011-0970-1
[3] THOMAS R HENSON. R-DOTAP Cationic Lipid Nanoparticles Outperform Squalene-Based Adjuvant Systems in Elicitation of CD4 T Cells after Recombinant Influenza Hemagglutinin Vaccination.[J]. Viruses-Basel, 2023, 15 2. DOI: 10.3390/v15020538 |
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