| Hazard Information | Back Directory | [Description]
YKAs3003 is a novel potent inhibitor of pathogenic KAS III. This antimicrobial compound displays minimal inhibitory concentration (MIC) values in the range 128-256 microg/mL against various bacteria. | [Uses]
YKAs3003 is a potent inhibitor of Escherichia coli KAS III (ecKAS III) with antibacterial activity. The minimum inhibitory concentrations (MICs) of YKAs3003 against a variety of bacteria ranged from 128 to 256 μg/mL[1]. | [References]
[1] Lee J Y, et al. Novel E. coli β-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics[J]. Bioorganic & Medicinal Chemistry, 2009, 17(4): 1506-1513. DOI:10.1016/j.bmc.2009.01.004 |
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