ChemicalBook--->CAS DataBase List--->329187-86-2

329187-86-2

329187-86-2 Structure

329187-86-2 Structure
IdentificationBack Directory
[Name]

2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
[CAS]

329187-86-2
[Synonyms]

2'-F-2'-ara-Bz-dA Phosphoramidite
2'-F-dA(Bz)-ANA-CE Phosphoramidite
2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
N6-Bz-5'-O-DMTr-2'-fluoro-2'-deoxyarabinoadenosine-3'-CED-phosphoramidite
5'-O-DMT-N6-Benzoyl-2'-fluoro-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite
5'-O-DMT-2'-Fluoro-N6-Benzoyl-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyarabino adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-9H-purin-6-yl]-
N6-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-fluoro-2’-deoxyarabinoadenosine-3’-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite, 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite
[Molecular Formula]

C47H51FN7O7P
[MOL File]

329187-86-2.mol
[Molecular Weight]

875.94
Chemical PropertiesBack Directory
[solubility ]

DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
[form ]

Solid
[pka]

8.80±0.10(Predicted)
[color ]

White to off-white
[InChIKey]

VCCMVPDSLHFCBB-JGVLZJSQNA-N
[SMILES]

C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=NC3=C(N=CN=C23)NC(C2C=CC=CC=2)=O)[C@@H](F)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,46,48,r|
Hazard InformationBack Directory
[Uses]

2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite (2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite) is a phosphoramidite monomer used to synthesize special oligonucleotides or modified DNA derivatives.
[References]

[1] T. TENNILÄ. Oligonucleotides Containing 9-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-Adenine and -Guanine: Synthesis, Hybridization and Antisense Properties[J]. Nucleosides, Nucleotides & Nucleic Acids, 2000, 19 1: 1861-1884. DOI: 10.1080/15257770008045466
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