| Identification | Back Directory | [Name]
Guanidine, N-[(2S,3S,4R)-6-amino-2-(dimethoxymethyl)-3,4-dihydro-3-hydroxy-2-methyl-2H-1-benzopyran-4-yl]-N'-cyano-N''-(phenylmethyl)- | [CAS]
335381-68-5 | [Synonyms]
DNB001
DNB-001
KR31378
DNB 001
MSH1001
MSH-1001
KR-31378
Guanidine, N-[(2S,3S,4R)-6-amino-2-(dimethoxymethyl)-3,4-dihydro-3-hydroxy-2-methyl-2H-1-benzopyran-4-yl]-N'-cyano-N''-(phenylmethyl)- | [Molecular Formula]
C22H27N5O4 | [MOL File]
335381-68-5.mol | [Molecular Weight]
425.48 |
| Hazard Information | Back Directory | [Uses]
KR-31378 is a neuroprotectant with dose-dependent pharmacokinetic properties and relevant activity in rats. After intravenous and oral administration of KR-31378 in rats, its pharmacokinetic parameters showed dose-dependent changes, such as decreased clearance with increasing doses, good oral absorption, and comparable AUCs for intravenous and oral administration at different doses. | [References]
[1] Dose-dependent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31378, in rats |
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