| Identification | Back Directory | [Name]
nifurfoline | [CAS]
3363-58-4 | [Synonyms]
nifurfoline
3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin
3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione | [EINECS(EC#)]
222-131-4 | [Molecular Formula]
C13H15N5O6 | [MDL Number]
MFCD00864944 | [MOL File]
3363-58-4.mol | [Molecular Weight]
337.29 |
| Hazard Information | Back Directory | [Originator]
Furobactil,Carrion,France,1974
| [Definition]
ChEBI: Nifurfoline is an imidazolidine-2,4-dione. | [Manufacturing Process]
20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the
solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc
of 40% formaldehyde are added, followed by 10 g of freshly distilled
morpholine. The heating is continued for one hour, the mixture cooled and
filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the
desired product are obtained as yellow crystals which melt at 206°C. | [Therapeutic Function]
Antibacterial |
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