| Identification | Back Directory | [Name]
3-AMINO-4-METHOXYPYRIDINE | [CAS]
33631-09-3 | [Synonyms]
CBI-BB ZERO/004846
4-Methoxy-3-PyridinaMine
3-AMINO-4-METHOXYPYRIDINE
3-Pyridinamine, 4-methoxy-
4-METHOXY-PYRIDIN-3-YLAMINE
3-Amino-4-methoxypyridine ,98%
3-AMINO-4-METHOXYPYRIDINE ISO 9001：2015 REACH | [Molecular Formula]
C6H8N2O | [MDL Number]
MFCD07374959 | [MOL File]
33631-09-3.mol | [Molecular Weight]
124.14 |
| Chemical Properties | Back Directory | [Melting point ]
83 °C | [Boiling point ]
270.4±20.0 °C(Predicted) | [density ]
1.139±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
solid | [pka]
7.48±0.18(Predicted) | [color ]
Brown | [InChI]
InChI=1S/C6H8N2O/c1-9-6-2-3-8-4-5(6)7/h2-4H,7H2,1H3 | [InChIKey]
STWMPIWLSQKHSJ-UHFFFAOYSA-N | [SMILES]
C1=NC=CC(OC)=C1N |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white solid | [Synthesis]
Example 93: Synthesis of 4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxylic acid (7-methoxy-thiazolo[5,4-b]pyridin-2-yl)-amide; Step 1: To a solution of 4-methoxy-3-nitropyridine (5.0 g, 32.44 mmol) in ethanol (100 mL) was added 10% palladium/carbon catalyst (200 mg). The reaction mixture was placed under hydrogen atmosphere (50 psi) and the reaction was shaken at room temperature for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, 50% ethyl acetate/hexane) to confirm complete conversion of the feedstock. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated under reduced pressure to afford 3-amino-4-methoxypyridine (4.0 g, 32.44 mmol, 100% yield), the product was a dark red oil. | [References]
[1] Patent: US2007/270433, 2007, A1. Location in patent: Page/Page column 47
[2] Patent: WO2012/67664, 2012, A1. Location in patent: Page/Page column 53
[3] Inorganic Chemistry, 2013, vol. 52, # 7, p. 3653 - 3662
[4] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 49-50
[5] Chemistry - A European Journal, 2012, vol. 18, # 51, p. 16358 - 16368 |
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