| Identification | Back Directory | [Name]
3-MORPHOLINOSYDNONIMINE | [CAS]
33876-97-0 | [Synonyms]
SIN-1
cv664
Sin-1 16142-27-1
3-MORPHOLINOSYDNONIMINE
3-morpholinosydnoneimine
3-MorpholinosydnonmineHCl
3-Morpholinosydnone imine-3-ium
3-Morpholinosydnonminehydrochloride
Molsidomine Impurity 1 (Molsidomine EP Impurity A)
3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine
SIN-1 HYDROCHLORIDE (3-MORPHOLINOSYDNONI MINEHYDROCHLORIDE, LINSID
3-(4-Morpholinyl)sydnone imine hydrochloride, Linsidomine hydrochloride, SIN-1 hydrochloride | [Molecular Formula]
C6H10N4O2 | [MDL Number]
MFCD00214332 | [MOL File]
33876-97-0.mol | [Molecular Weight]
170.17 |
| Hazard Information | Back Directory | [Uses]
3-Morpholinosydnonimine is a potent vasodilator that inhibits platelet aggregation and cysteine proteases. | [Definition]
ChEBI:Linsidomine is a member of morpholines. | [in vivo]
3-Morpholinosydnonimine (0.01-0.1 mg/kg; 14 days) attenuates neointima formation in balloon-injured rat carotid arteries[4]. | Animal Model: | Six-week-old male Sprague Dawley rats (180-190 g) with a balloon-injured carotid artery model[4] | | Dosage: | 0.01 and 0.1 mg/kg/day | | Administration: | 14 days | | Result: | Reduced the I/M (intima to media) ratio of the carotid artery in the group treated with 0.1 mg/kg/day.
Did not change the I/M ratio of the carotid artery in the group treated with 0.01 mg/kg/day.
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| [IC 50]
AnxA2 |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|