339306-30-8

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339306-30-8 Structure

Identification	Back Directory
[Name] Lorvotuzumab (anti-CD56)
[CAS] 339306-30-8
[Synonyms] Lorvotuzumab (anti-CD56)

Chemical Properties	Back Directory
[form ] Liquid
[color ] Colorless to light yellow

Hazard Information	Back Directory
[Uses] Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds CD56 (NCAM1). Lorvotuzumab can be used to synthesize an ADC compound, Lorvotuzumab mertansine[1].
[References] [1] James I Geller, et al. ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study. Cancer. 2020 Dec 15;126(24):5303-5310. DOI:10.1002/cncr.33195

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