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34168-56-4

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34168-56-4 Structure

34168-56-4 Structure
IdentificationBack Directory
[Name]

Catalpol
[CAS]

34168-56-4
[Synonyms]

Catalponol
Catalpol USP/EP/BP
1(2H)-Naphthalenone,3,4-dihydro-4-hydroxy- 2-(3-methyl-2-butenyl)-,(2R,4S)-
1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-buten-1-yl)-, (2R,4S)-
[Molecular Formula]

C15H18O2
[MOL File]

34168-56-4.mol
[Molecular Weight]

230.3
Chemical PropertiesBack Directory
[Boiling point ]

369.8±31.0 °C(Predicted)
[density ]

1.095±0.06 g/cm3(Predicted)
[pka]

13.79±0.40(Predicted)
[CAS DataBase Reference]

34168-56-4
Hazard InformationBack Directory
[Uses]

Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].
[References]

[1] Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. DOI:10.1080/10286020903193094
[2] Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. DOI:10.1007/s12272-010-0306-2
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