| Identification | Back Directory | [Name]
Tenofovir Related Compound 1 | [CAS]
342631-41-8 | [Synonyms]
TAF-IM-D1
TAF Impurity A
TAF Impurity 4
Tenofovir alafenamide-5
enofovir Related Compound 1
Tenofovir related Impurity 2
Tenofovir Related Compound 1
Tenofovir Alafenamide Impurity A
Tenofovir Alafenamide Impurity 1
6-amido-9-[(2R)-2-(diphenyl phosphoryl methoxy)Propyl]purine
diphenyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Tenofovir impurity 28/6-amido-9-[(2R)-2-(diphenyl phosphoryl methoxy)Propyl]purine
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, diphenyl ester (9CI) | [Molecular Formula]
C21H22N5O4P | [MDL Number]
MFCD29919180 | [MOL File]
342631-41-8.mol | [Molecular Weight]
439.4 |
| Chemical Properties | Back Directory | [Boiling point ]
636.3±65.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [solubility ]
Chloroform (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
4.21±0.10(Predicted) | [color ]
White to Pale Beige | [InChIKey]
XWTDSRIRFPGRAW-MRXNPFEDSA-N | [SMILES]
C(P(=O)(OC1=CC=CC=C1)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2 |
| Hazard Information | Back Directory | [Uses]
(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate is a reagent for the synthesis of amidate prodrugs of PMEA and PMPA. Also functions as a reagent in the preparation of tenofovir alafenamide fumarate impurity. |
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