| Identification | Back Directory | [Name]
UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) | [CAS]
342878-90-4 | [Synonyms]
URP, HUMAN, RAT
URP (HUMAN, MOUSE, RAT)
UIIB (HUMAN, MOUSE, RAT)
UROTENSIN II-RELATED PEPTIDE
M.W. 1017.23 C49H64N10O10S2
ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL
UROTENSIN IIB (HUMAN, MOUSE, RAT)
H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH
UROTENSIN II RELATED PEPTIDE, HUMAN, RAT
ACFWKYCV( Disulfide bridge between 2 - 7)
UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)
UROTENSIN II-RELATED PEPTIDE (HUMAN, RAT) (MOUSE)
H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, (DISULFIDE BOND)
Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge Cys2-Cys7)
UIIB (huMan, Mouse, rat), Urotensin IIB (huMan, Mouse, rat), URP (huMan, Mouse, rat) | [Molecular Formula]
C49H64N10O10S2 | [MDL Number]
MFCD06656090 | [MOL File]
342878-90-4.mol | [Molecular Weight]
1017.22 |
| Chemical Properties | Back Directory | [Boiling point ]
1424.2±65.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 1 mg/ml in 5% acetonitrile / sterile water | [form ]
Powder | [pka]
3.60±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge:Cys2-Cys7) |
| Hazard Information | Back Directory | [Description]
Potent endogenous agonist for the urotensin-II (UT) receptor. Binds with high affinity and potently activates recombinant rat and human UT receptors (EC50 values are 0.55 and 4.8 nM respectively). Produces hypotensive effects following systemic administration in rats. | [Uses]
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor[1][2]. | [storage]
Desiccate at -20°C | [References]
[1] Lescot E, et al. Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships Peptides. 2008 May;29(5):680-90. DOI:10.1016/j.peptides.2007.09.019
[2] Labarrère P, et al. Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction. J Enzyme Inhib Med Chem. 2003 Apr;18(2):77-88. DOI:10.1080/1475636031000093507 |
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