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342878-90-4

342878-90-4 Structure

342878-90-4 Structure
IdentificationBack Directory
[Name]

UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)
[CAS]

342878-90-4
[Synonyms]

URP, HUMAN, RAT
URP (HUMAN, MOUSE, RAT)
UIIB (HUMAN, MOUSE, RAT)
UROTENSIN II-RELATED PEPTIDE
M.W. 1017.23 C49H64N10O10S2
ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL
UROTENSIN IIB (HUMAN, MOUSE, RAT)
H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH
UROTENSIN II RELATED PEPTIDE, HUMAN, RAT
ACFWKYCV( Disulfide bridge between 2 - 7)
UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)
UROTENSIN II-RELATED PEPTIDE (HUMAN, RAT) (MOUSE)
H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, (DISULFIDE BOND)
Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge Cys2-Cys7)
UIIB (huMan, Mouse, rat), Urotensin IIB (huMan, Mouse, rat), URP (huMan, Mouse, rat)
[Molecular Formula]

C49H64N10O10S2
[MDL Number]

MFCD06656090
[MOL File]

342878-90-4.mol
[Molecular Weight]

1017.22
Chemical PropertiesBack Directory
[Boiling point ]

1424.2±65.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[storage temp. ]

Desiccate at -20°C
[solubility ]

Soluble to 1 mg/ml in 5% acetonitrile / sterile water
[form ]

Powder
[pka]

3.60±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Potent endogenous agonist for the urotensin-II (UT) receptor. Binds with high affinity and potently activates recombinant rat and human UT receptors (EC50 values are 0.55 and 4.8 nM respectively). Produces hypotensive effects following systemic administration in rats.
[Uses]

Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor[1][2].
[storage]

Desiccate at -20°C
[References]

[1] Lescot E, et al. Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships Peptides. 2008 May;29(5):680-90. DOI:10.1016/j.peptides.2007.09.019
[2] Labarrère P, et al. Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction. J Enzyme Inhib Med Chem. 2003 Apr;18(2):77-88. DOI:10.1080/1475636031000093507
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