343268-91-7

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343268-91-7 Structure

Chemical Properties	Back Directory
[Boiling point ] 2099.4±65.0 °C(Predicted)
[density ] 1.287±0.06 g/cm3(Predicted)
[storage temp. ] Store at -20°C
[form ] Powder
[pka] 4.42±0.10(Predicted)
[color ] White to off-white
[Water Solubility ] Soluble to 1 mg/ml in water

Hazard Information	Back Directory
[Uses] OXA(17-33) is a potent and selective orexin-1 receptor (OX1) agonist. OXA(17-33) shows a ～23-fold selectivity for the OX1 (EC50=8.29 nM) over OX2 (187 nM)[1].
[IC 50] OX1: 8.29 nM (EC₅₀); OX2: 187 nM (EC₅₀)
[storage] Store at -20°C
[References] [1] German NA, et al. Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 2013;4(12):1224-1227. DOI:10.1021/ml400333a

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