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34487-26-8

34487-26-8 Structure

34487-26-8 Structure
IdentificationBack Directory
[Name]

1-stearoyl-2-linoleoyl-sn-glycerol
[CAS]

34487-26-8
[Synonyms]

9,12-Octadecadienoic acid (9Z,12Z)-, (1S)-1-(hydroxymethyl)-2-[(1-oxooctadecyl)oxy]ethyl ester
[Molecular Formula]

C39H72O5
[MOL File]

34487-26-8.mol
[Molecular Weight]

620.99
Chemical PropertiesBack Directory
[Boiling point ]

670.2±35.0 °C(Predicted)
[density ]

0.934±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Ethyl Acettate (Slightly)
[form ]

Oil
[pka]

13.69±0.10(Predicted)
[color ]

Colourless
[Stability:]

Light Sensitive, Moisture Sensitive, Temperature Sensitive
[InChIKey]

AJMZUFBKADIAKC-SKTOPKGQSA-N
[SMILES]

O([C@H](COC(=O)CCCCCCCCCCCCCCCCC)CO)C(=O)CCCCCCC\C=C/C\C=C/CCCCC
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Hazard Classifications]

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
Hazard InformationBack Directory
[Uses]

1-Stearoyl-2-linoleoyl-sn-glycerol is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator.
[Definition]

ChEBI: A 1,2-diacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as stearoyl and linoleoyl respectively.
[Biological Activity]

DAG plays a vital role in the physiological activation of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane. Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.
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