| Identification | Back Directory | [Name]
SUN B8155 | [CAS]
345893-91-6 | [Synonyms]
SUN B-8155,SUN B8155
5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone | [Molecular Formula]
C14H15N3O3 | [MDL Number]
MFCD08276926 | [MOL File]
345893-91-6.mol | [Molecular Weight]
273.29 |
| Chemical Properties | Back Directory | [Boiling point ]
419.0±55.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥5 mg/mL | [form ]
solid | [pka]
0.77±0.58(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
SUN-B 8155 is a pyridone derivative and a selective calcitonin receptor agonist (1). SUN-B 8155 has been shown to lower serum calcium levels in rats. | [Biological Activity]
Non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC 50 = 21 μ M). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration. | [in vivo]
SUN B8155 (100 mg/kg; i.p.) results in a significant reduction of serum calcium concentration by approximately 9% at 30 min after administration. Human CT also reduces serum calcium in a dose-dependent manner at 30 min (0.1 and 0.3 μg/kg) and 60 min (0.3 μg/kg) after administration[1]. | [storage]
Store at +4°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310; |
| Website: |
https://www.weikeqi-biotech.com/ |
|