ChemicalBook--->CAS DataBase List--->345986-38-1

345986-38-1

345986-38-1 Structure

345986-38-1 Structure
IdentificationBack Directory
[Name]

2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
[CAS]

345986-38-1
[Synonyms]

2-Benzothiazoleacetonitrile, α-(2-chloro-4-pyrimidinyl)-
2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
[Molecular Formula]

C13H7ClN4S
[MOL File]

345986-38-1.mol
[Molecular Weight]

286.74
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively[1].
[IC 50]

JNK2: 500 nM (IC50); JNK3: 290 nM (IC50)
[References]

[1] Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.
Spectrum DetailBack Directory
[Spectrum Detail]

2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile(345986-38-1)1HNMR
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