| Identification | Back Directory | [Name]
N-(4-butylphenyl)-5-nitrofuran-2-carboxamide | [CAS]
346691-38-1 | [Synonyms]
STING-IN-2
STING inhibitor C-170
N-(4-butylphenyl)-5-nitrofuran-2-carboxamide
2-Furancarboxamide, N-(4-butylphenyl)-5-nitro-
Inhibitor,autoinflammatory,STING,ERIS,MPYS,cGAMP,MITA,IFNB1,STING IN 2,Stimulator of Interferon Genes,TMEM173,inhibit,palmitoylation,STINGIN2,p-TBK1,TNF | [Molecular Formula]
C15H16N2O4 | [MDL Number]
MFCD00784211 | [MOL File]
346691-38-1.mol | [Molecular Weight]
288.3 |
| Chemical Properties | Back Directory | [Boiling point ]
359.3±37.0 °C(Predicted) | [density ]
1.260±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: Soluble | [form ]
A crystalline solid | [pka]
11.88±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research[1]. | [storage]
Store at -20°C | [References]
[1] Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. DOI:10.1038/s41586-018-0287-8 |
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