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347397-83-5

347397-83-5 Structure

347397-83-5 Structure
IdentificationBack Directory
[Name]

(5E)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione
[CAS]

347397-83-5
[Synonyms]

cp028
Compound028
Compound-028
Compound 028
(5E)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione
(5Z)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione
[Molecular Formula]

C23H17FN2O4
[MOL File]

347397-83-5.mol
[Molecular Weight]

404.39
Chemical PropertiesBack Directory
[density ]

1.347±0.06 g/cm3(Predicted)
[pka]

7.16±0.20(Predicted)
Hazard InformationBack Directory
[Description]

cp028 is an inhibitor of pre-mRNA splicing in vitro.
[Uses]

cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 μM[1].
[References]

[1] Sidarovich A, et al. Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. Elife. 2017 Mar 16;6:e23533. DOI:10.7554/eLife.23533
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