| Chemical Properties | Back Directory | [Boiling point ]
1146.503±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.384±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
4.031±0.10(predicted) | [Sequence]
Z-Ile-Glu-Thr-Asp-pNA |
| Hazard Information | Back Directory | [Uses]
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA[1]. | [References]
[1] Yu-Hsuan Lan, et al. Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells. Oncol Rep. 2011 Feb;25(2):419-24. DOI:10.3892/or.2010.1087 |
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