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34840-28-3

34840-28-3 Structure

34840-28-3 Structure
IdentificationBack Directory
[Name]

Formamide, N-(2-aminophenyl)-
[CAS]

34840-28-3
[Synonyms]

HDAC ligand-1
Formamide, N-(2-aminophenyl)-
[Molecular Formula]

C7H8N2O
[MOL File]

34840-28-3.mol
[Molecular Weight]

136.15
Chemical PropertiesBack Directory
[Boiling point ]

358.0±25.0 °C(Predicted)
[density ]

1.254±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

14.61±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

HDAC ligand-1 is a HDAC ligand that can be used to synthesize PROTAC HDAC degraders, such as compounds 21a and 21b in references[1].
[References]

[1] Yingxin Lu, et al. Design, Synthesis, and Biological Evaluation of HDAC Degraders with CRBN E3 Ligase Ligands. Molecules. 2021 Nov 29;26(23):7241. DOI:10.3390/molecules26237241
34840-28-3 suppliers list
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