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349438-74-0

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349438-74-0 Structure

349438-74-0 Structure
IdentificationBack Directory
[Name]

N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
[CAS]

349438-74-0
[Synonyms]

WAY-296817
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
[Molecular Formula]

C17H16N2O3S
[MOL File]

349438-74-0.mol
[Molecular Weight]

328.39
Chemical PropertiesBack Directory
[density ]

1.323±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

10.22±0.70(Predicted)
[color ]

Gray to brown
Hazard InformationBack Directory
[Uses]

CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 μM for CK-1δ[1][2].
[in vivo]

CK1-IN-3 (compound 35) (100 nM; feed) significantly extendes fly lifespan to 36.17 days[2].

[IC 50]

CK1δ: 2.22 μM (IC50)
[References]

[1] Ana MARTíNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1.
[2] Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57(6):2755-72. DOI:10.1021/jm500065f
Spectrum DetailBack Directory
[Spectrum Detail]

N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide(349438-74-0)1HNMR
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