| Identification | Back Directory | [Name]
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- | [CAS]
350509-85-2 | [Synonyms]
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- | [Molecular Formula]
C13H12N2O4S | [MOL File]
350509-85-2.mol | [Molecular Weight]
292.31 |
| Hazard Information | Back Directory | [Uses]
ERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12 exhibits anti-cancer activity and can be utilized in cancer research[1]. | [References]
[1] Boston SR, et al. Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer. 2011 Jan 10;11:7. DOI:10.1186/1471-2407-11-7 |
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