| Identification | Back Directory | [Name]
4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide | [CAS]
351520-91-7 | [Synonyms]
2002-H20
2002-H20 >=98% (HPLC)
4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide | [Molecular Formula]
C20H15N3O3 | [MDL Number]
MFCD00852780 | [MOL File]
351520-91-7.mol | [Molecular Weight]
345.35 |
| Chemical Properties | Back Directory | [Boiling point ]
500.5±50.0 °C(Predicted) | [density ]
1.412±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥15mg/mL | [form ]
powder | [pka]
8.79±0.50(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
2002-H20 is an inhibitor of Aβ42-induced cytotoxicity, with the activity of reducing the cytotoxicity of Alzheimer's disease Aβ peptide by binding to it. 2002-H20 protects cells and reduces Aβ toxicity by promoting fibril formation, possibly by accelerating Aβ aggregation. The screening method of 2002-H20 effectively identifies compounds that reduce Aβ toxicity and presents potential inhibitory leads[1]. | [Definition]
ChEBI: 4-amino-N-[3-(3H-1,3-benzoxazol-2-ylidene)-4-oxo-1-cyclohexa-1,5-dienyl]benzamide is a member of benzamides. | [References]
[1] Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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