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353250-09-6

353250-09-6 Structure

353250-09-6 Structure
IdentificationBack Directory
[Name]

N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
[CAS]

353250-09-6
[Synonyms]

N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
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[Uses]

ERK2 IN-5 (Compound 5g) is an inhibitor for ERK2, and exhibits good affinity to ERK2 and JNK3 with Ki of 86 and 550 nM[1].
[IC 50]

ERK2: 86 nM (Ki); JNK3: 550 nM (Ki)
[References]

[1] Aronov AM, et al., Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors. J Med Chem. 2007 Mar 22;50(6):1280-7. DOI:10.1021/jm061381f
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