| Identification | Back Directory | [Name]
2-Amino-6-chlorobenzaldehyde | [CAS]
35490-90-5 | [Synonyms]
2-Amino-6-chlorobenzaldehyde
Benzaldehyde, 2-amino-6-chloro-
2-Amino-6-chlorobenzaldehyde ISO 9001：2015 REACH | [Molecular Formula]
C7H6ClNO | [MDL Number]
MFCD10696880 | [MOL File]
35490-90-5.mol | [Molecular Weight]
155.58 |
| Chemical Properties | Back Directory | [Boiling point ]
290.3±25.0 °C(Predicted) | [density ]
1.348±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
-0.70±0.10(Predicted) | [Appearance]
Light yellow to yellow Solid | [InChI]
InChI=1S/C7H6ClNO/c8-6-2-1-3-7(9)5(6)4-10/h1-4H,9H2 | [InChIKey]
RNEANOJBDLVBRF-UHFFFAOYSA-N | [SMILES]
C(=O)C1=C(Cl)C=CC=C1N |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 2-amino-6-chlorobenzaldehyde from (2-amino-6-chlorophenyl)-methanol: Manganese dioxide (13.6 g, 157 mmol) was added to a solution of 2-amino-6-chlorophenylmethanol (2.75 g, 17.5 mmol) dissolved in 150 mL diethyl ether. The reaction mixture was stirred at room temperature for 0.5 h, followed by filtration through a diatomaceous earth pad and washed well with ethyl acetate. The filtrate was concentrated under reduced pressure to give 2.62 g (96% yield) of 2-amino-6-chlorobenzaldehyde as a pale yellow solid. | [References]
[1] Patent: WO2006/10142, 2006, A2. Location in patent: Page/Page column 70; 71
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831
[3] ChemistryOpen, 2015, vol. 4, # 2, p. 107 - 110
[4] Patent: US2018/105527, 2018, A1. Location in patent: Paragraph 0786-0788
[5] Organic and Biomolecular Chemistry, 2016, vol. 14, # 38, p. 8966 - 8970 |
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