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355428-84-1

355428-84-1 Structure

355428-84-1 Structure
IdentificationBack Directory
[Name]

3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-butenyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
[CAS]

355428-84-1
[Synonyms]

3HOIBA01
3HOI BA 01
3HOI-BA-01
3-HOI-BA-01
3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-butenyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
[Molecular Formula]

C19H15NO5
[MOL File]

355428-84-1.mol
[Molecular Weight]

337.326
Hazard InformationBack Directory
[Uses]

3HOI-BA-01 is amTORinhibitor.3HOI-BA-01reduces infarct size and inducedautophagyin a murine myocardial ischemia/reperfusion injury model[1].
[References]

[1] Huang L, et al. The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy. J Cardiovasc Pharmacol Ther. 2016;21(1):70-81. DOI:10.1177/1074248415581177
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