| Identification | Back Directory | [Name]
6,6-BIS(4-CARBOXY-2-OXABUTYL)-4,8-DIOXAUNDECANE-1, 11-DICARBOXYLIC ACID | [CAS]
35638-19-8 | [Synonyms]
TETRAACID
6,6-BIS(4-CARBOXY-2-OXABUTYL)-4,8-DIOXAUNDECANE-1, 11-DICARBOXYLIC ACID
3-[3-(2-carboxyethoxy)-2,2-bis(2-carboxyethoxymethyl)propoxy]propanoic acid
3,3'-((2,2-Bis((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropanoic acid
3,3'-((2,2-bis((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid
Propanoic acid, 3,3'-[[2,2-bis[(2-carboxyethoxy)methyl]-1,3-propanediyl]bis(oxy)]bis- | [Molecular Formula]
C17H28O12 | [MDL Number]
MFCD08669605 | [MOL File]
35638-19-8.mol | [Molecular Weight]
424.4 |
| Chemical Properties | Back Directory | [Melting point ]
98-101 °C(Solv: acetonitrile (75-05-8)) | [Boiling point ]
710.3±60.0 °C(Predicted) | [density ]
1.355±0.06 g/cm3(Predicted) | [storage temp. ]
Store at room temperature | [form ]
solid | [pka]
3.66±0.10(Predicted) | [color ]
White | [InChI]
InChI=1S/C17H28O12/c18-13(19)1-5-26-9-17(10-27-6-2-14(20)21,11-28-7-3-15(22)23)12-29-8-4-16(24)25/h1-12H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25) | [InChIKey]
KIGSIPUDIPIMRD-UHFFFAOYSA-N | [SMILES]
C(OCCC(O)=O)C(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O |
| Hazard Information | Back Directory | [Description]
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a 4-branched molecule with carboxylic acid groupss to be conjugate with amino groups of other molecule or entity. | [Uses]
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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