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35683-17-1

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35683-17-1 Structure

35683-17-1 Structure
IdentificationBack Directory
[Name]

Dihydrobaicalein
[CAS]

35683-17-1
[Synonyms]

Dihydrobaicalein
[Molecular Formula]

C15H12O5
[MOL File]

35683-17-1.mol
[Molecular Weight]

272.25
Chemical PropertiesBack Directory
[Melting point ]

226-227 °C
[Boiling point ]

595.0±50.0 °C(Predicted)
[density ]

1.485±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

7.34±0.40(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Description]

Dihydrobaicalein is a natural product from Scutellaria baicalensis Georgi.
[Uses]

Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].
[IC 50]

PLK1
[References]

[1] Woo SU, et al. 7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells. Planta Med. 2019 Feb;85(3):217-224. DOI:10.1055/a-0731-0394
Spectrum DetailBack Directory
[Spectrum Detail]

Dihydrobaicalein(35683-17-1)1HNMR
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