| Identification | Back Directory | [Name]
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one | [CAS]
358343-63-2 | [Synonyms]
hMAO-B-IN-5
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one
2-Propen-1-one, 1-(4-ethoxyphenyl)-3-[4-(phenylmethoxy)phenyl]- | [Molecular Formula]
C24H22O3 | [MDL Number]
MFCD01901528 | [MOL File]
358343-63-2.mol | [Molecular Weight]
358.43 |
| Chemical Properties | Back Directory | [Boiling point ]
546.405±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.138±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
hMAO-B-IN-5(B15) is a potent, selective and reversible inhibitor of human monoamine oxidase hMAO-B with IC50 of 0.12 μM. hMAO-B-IN-5 can pass through the blood-brain barrier and can be used in the research of neurodegenerative diseases[1]. | [References]
[1] Sachithra Thazhathuveedu Sudevan, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404. DOI:10.1038/s41598-022-26929-x |
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| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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