| Identification | Back Directory | [Name]
3-Hydroxy-11-ursen-28,13-olide | [CAS]
35959-05-8 | [Synonyms]
13-olide
Ehretiolide
3-Hydroxy-11-ursen-28
3-Hydroxy-11-ursen-28,13-olide
3β-Hydroxyurs-11-en-28,13-olide
3β-Hydroxyurs-11-en-28,13-olide
3β-Hydroxyurs-11-en-28,13β-olide
3beta-Hydroxy-urs-11-en 28,13-lactone
Ehretiolide/3-Hydroxy-11-ursen-2813-olide | [Molecular Formula]
C30H47O3 | [MDL Number]
MFCD11975528 | [MOL File]
35959-05-8.mol | [Molecular Weight]
456 |
| Chemical Properties | Back Directory | [Melting point ]
262-265 °C | [Boiling point ]
563.1±50.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
15.15±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
3β-Hydroxy-urs-11-en-28,13β-olide exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line.
3β-Hydroxy-urs-11-en-13β,28-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line?relative to silymarin as a reference standard. | [Uses]
3β-Hydroxyurs-11-en-28,13β-olide (11,12-Dehydroursolic acid lactone) is a triterpenoid that can be found in Fadogia tetraquetra var. tetraquetra[1]. 3β-Hydroxyurs-11-en-28,13β-olide shows antibacterial activity[1]. | [References]
[1] Mulholland DA, et al. Triterpenoid acids and lactones from the leaves of Fadogia tetraquetra var. tetraquetra (Rubiaceae). Nat Prod Commun. 2011 Nov;6(11):1573-6. PMID:22224262 |
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BioBioPha Co., Ltd.
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