ChemicalBook--->CAS DataBase List--->359784-84-2

359784-84-2

359784-84-2 Structure

359784-84-2 Structure
IdentificationBack Directory
[Name]

[Ala17]-MCH
[CAS]

359784-84-2
[Synonyms]

[Ala17]-MCH
[Molecular Formula]

C97H155N29O26S4
[MDL Number]

MFCD12912478
[MOL File]

359784-84-2.mol
[Molecular Weight]

2271.71
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 2 mg/ml in water
[Sequence]

Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Ala-Gln-Val (Disulfide bridge:Cys7-Cys16)
Hazard InformationBack Directory
[Uses]

[Ala17]-MCH, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2[1].
[storage]

Store at -20°C
[References]

[1] Xiaoying Gao, et al. Europium-labeled melanin-concentrating hormone analogues: ligands for measuring binding to melanin-concentrating hormone receptors 1 and 2. Anal Biochem. 2004 May 15;328(2):187-95. DOI:10.1016/j.ab.2004.01.017
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