ChemicalBook--->CAS DataBase List--->3600-87-1

3600-87-1

3600-87-1 Structure

3600-87-1 Structure
IdentificationBack Directory
[Name]

2-Amino-1-(2,5-dimethoxyphenyl)ethanol
[CAS]

3600-87-1
[Synonyms]

ST 1059
DE-GLYMIDODRINE
DESGLYMIDODRINE
ST 1059(Desglymidodrine)
Midodrine Related CoMpound A
de-GlyMidodrine, DesglyMidodrine
2,5-Dimethoxyphenyl-2-hydroxyethylamine
1-(2',5'-DIMETHOXYPHENYL)-2-AMINOETHANOL
2-AMINO-1-(2,5-DIMETHOXY-PHENYL)-ETHANOL
2-aMino-1-(2,5-diMethoxyphenyl)ethan-1-ol
2-Amino-1-(2,5-dimethoxyphenyl)ethanol HCl
α-(AMinoMethyl)-2,5-diMethoxy-benzyl Alcohol
α-(AMinoMethyl)-2,5-diMethoxy-benzeneMethanol
Midodrine Related CoMpound A (DesglyMidodrine)
alpha-(Aminomethyl)-2,5-dimethoxybenzyl alcohol
ST 10591-(2',5'-DIMETHOXYPHENYL)-2-AMINOETHANOL
1-(25Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine
Midodrine Related Compound A (40 mg) (2-amino-1-(2,5-dimethoxyphenyl)ethanol)
ST 1059 1-(25Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine
2-Amino-1-(2,5-dimethoxyphenyl)ethan-1-ol, 2,5-Dimethoxy-beta-hydroxyphenethylamine
[EINECS(EC#)]

868-039-3
[Molecular Formula]

C10H15NO3
[MDL Number]

MFCD03701227
[MOL File]

3600-87-1.mol
[Molecular Weight]

197.23
Chemical PropertiesBack Directory
[Appearance]

White Powder
[Melting point ]

146-150°C dec.
[Boiling point ]

364.3±42.0 °C(Predicted)
[density ]

1.145±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly, Sonicated), Methanol (Slightly)
[form ]

Solid
[pka]

11.84±0.35(Predicted)
[color ]

White to Off-White
[Major Application]

pharmaceutical
[InChI]

InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3
[InChIKey]

VFRCNXKYZVQYLX-UHFFFAOYSA-N
[SMILES]

C1(C(O)CN)C=C(C=CC=1OC)OC
Hazard InformationBack Directory
[Chemical Properties]

White Powder
[Uses]

A metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects
[Definition]

ChEBI: An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-amino-1-hydroxyethyl group. The immediate and active metabolite of midrodine, it is a direct-acting sympathomimetic with selective alpha-adrenergic agon st activity. Midrodine is used (generally as its hydrochloride salt) as a prodrug for deglymidodrine, which acts as a peripheral vasoconstrictor in the treatment of certain hypotensive states.
[IC 50]

α1A-adrenergic receptor: 5.89 (pKi); α1B-adrenergic receptor: 5.16 (pKi); rat alpha1D-adrenergic receptor: 5.78 (pKi); human α2A-adrenoceptor: 5.83 (pKi)
Safety DataBack Directory
[WGK Germany ]

WGK 3
[REACH Registrations]

Active
[HS Code ]

2922199695
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

STOT SE 1
Spectrum DetailBack Directory
[Spectrum Detail]

2-Amino-1-(2,5-dimethoxyphenyl)ethanol(3600-87-1)1HNMR
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