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360775-96-8

360775-96-8 Structure

360775-96-8 Structure
IdentificationBack Directory
[Name]

2-Hydroxymethyl-6-[2-(4-methoxy-benzyl)-phenoxy]-tetrahydro-pyran-3,4,5-triol
[CAS]

360775-96-8
[Synonyms]

Sergliflozin A
β-D-Glucopyranoside, 2-[(4-methoxyphenyl)methyl]phenyl
2-Hydroxymethyl-6-[2-(4-methoxy-benzyl)-phenoxy]-tetrahydro-pyran-3,4,5-triol
[Molecular Formula]

C20H24O7
[MOL File]

360775-96-8.mol
[Molecular Weight]

376
Chemical PropertiesBack Directory
[Melting point ]

94.8-95.5 °C
[Boiling point ]

590.7±50.0 °C(Predicted)
[density ]

1.344±0.06 g/cm3(Predicted)
[solubility ]

Acetonitrile: Slightly Soluble: 0.1-1 mg/ml
DMSO: Sparingly Soluble: 1-10 mg/ml
[pka]

12.82±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Sergliflozin-A is a compound used to inhibit type 2 diabetes. It can inhibit glucose transporters in the kidney, competitively inhibit hSGLT1 and hSGLT2, and mutations at different sites have different effects on its inhibitory effect.
[References]

[1] Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and?…
Spectrum DetailBack Directory
[Spectrum Detail]

2-Hydroxymethyl-6-[2-(4-methoxy-benzyl)-phenoxy]-tetrahydro-pyran-3,4,5-triol(360775-96-8)1HNMR
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