ChemicalBook--->CAS DataBase List--->362045-44-1

362045-44-1

362045-44-1 Structure

362045-44-1 Structure
IdentificationBack Directory
[Name]

Etimicin Sulphate
[CAS]

362045-44-1
[Synonyms]

Etimicin sulfate
EtiMycin Sulfate
Etimicin Sulphate
Etimicin Sulphate USP/EP/BP
Neti1micin Sulfate injection
O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4)]-2-deoxy-N1-ethyl-D-streptamine sulfate
[EINECS(EC#)]

1806241-263-5
[Molecular Formula]

C21H43N5O7.H2O4S
[MDL Number]

MFCD10566438
[MOL File]

362045-44-1.mol
[Molecular Weight]

575.677
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[InChIKey]

OEBISAUVQBGQKC-IMBHCJJFNA-N
Hazard InformationBack Directory
[Uses]

Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
[IC 50]

Aminoglycoside
[References]

[1] Yao L, Zhang JW, Chen B, et al. Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin. Acta Pharmacol Sin. 2020;41(6):866-878. DOI:10.1038/s41401-019-0342-5
[2] Shao W, Zhong D, Jiang H, et al. A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos. J Appl Toxicol. 2021;41(7):1063-1075. DOI:10.1002/jat.4093
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