Identification | Back Directory | [Name]
Etimicin Sulphate | [CAS]
362045-44-1 | [Synonyms]
Etimicin sulfate EtiMycin Sulfate Etimicin Sulphate Etimicin Sulphate USP/EP/BP Neti1micin Sulfate injection O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4)]-2-deoxy-N1-ethyl-D-streptamine sulfate | [EINECS(EC#)]
1806241-263-5 | [Molecular Formula]
C21H43N5O7.H2O4S | [MDL Number]
MFCD10566438 | [MOL File]
362045-44-1.mol | [Molecular Weight]
575.677 |
Hazard Information | Back Directory | [Uses]
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity. | [IC 50]
Aminoglycoside | [References]
[1] Yao L, Zhang JW, Chen B, et al. Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin. Acta Pharmacol Sin. 2020;41(6):866-878. DOI:10.1038/s41401-019-0342-5 [2] Shao W, Zhong D, Jiang H, et al. A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos. J Appl Toxicol. 2021;41(7):1063-1075. DOI:10.1002/jat.4093 |
|
|